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Lecturer(s)
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Spal Václav, doc. Mgr. CSc.
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Špilar Karel, Mgr. Ph.D.
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Course content
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1st practise Safety in the chemical laboratory. Practical introduction to semimicrotechnics, preparing of basic tools for working with small quanta. Determination of Koffler method, purity verification of compound by thin-flim chromatography. 2nd practise to 6th practise Basic synthesis of organic compounds (esterification, nitration, oxidation, reduction, diazotation, copulation, etc.). Isolation of product from the reaction mixture after synthesis. Isolation of organic compounds from natural material. Identification upcoming preparations. Note: Increased number of hours for lessons is used to include more time-consuming work focused on the synthesis and isolation from natural material.
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Learning activities and teaching methods
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Laboratory work
- Preparation for laboratory testing; outcome analysis (1-8)
- 8 hours per semester
- Contact hours
- 26 hours per semester
- Practical training (number of hours)
- 26 hours per semester
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| prerequisite |
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| Knowledge |
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| use the knowledge gained in LOCH1 |
| characterize the properties of specially processed and prepared chemicals |
| Skills |
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| respect the principles of safe work in micro and semimicro-scale |
| use special work techniques |
| describe the course and formulate the conclusions of the experiments |
| learning outcomes |
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| Knowledge |
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| to anticipate the course of chemical races based on knowledge of the properties of the reactants |
| to propose methods for identifying prepared products |
| modify known mechanisms for other compounds |
| Skills |
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| modify the working instructions to new technical conditions |
| choose a suitable isolation method |
| to identify prepared compounds by the chosen method |
| teaching methods |
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| Knowledge |
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| Laboratory work |
| assessment methods |
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| Skills demonstration during practicum |
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Recommended literature
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Klinotová, E.; Klinot, J.; Máca, B.; Trnka, T.; Všetečka, V. Základní cvičení z organické chemie. Praha: Univerzita Karlova, 1980.
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MAYO D. W., PIKE R. M., TRUMPER P. K. Microscale Techniques for the Organic Laboratory. John Wiley & sons, inc., New York, 2001. ISBN 0-471-24909-2.
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MOHRIG J. R., HAMMOND C. N., SCHATZ P. F., MORRILL T. C. Modern Projects and Experiments in Organic Chemistry. W. H. Freeman and Company, New York, 2003. ISBN 0-7167-9779-8.
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Richtr, Václav. Semimikrotechnika v organické chemii. 1. vyd. Plzeň : Pedagogická fakulta Západočeské univerzity, 1993. ISBN 80-7043-066-4.
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Trnka, Tomáš. Praktikum z organické chemie : Určeno pro posl. fak. přírodověd.. 1. vyd. Praha : SPN, 1986.
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