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Lecturer(s)
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Sedláčková Michaela, Ing.
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Course content
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Lectures 1. Contrast agents positive and negative used in radiodiagnostics, characteristics of individual groups. 2. Adverse toxic and allergic reactions after administration of contrast agent, prevention of side effects, treatment principles. 3. Contrast invasive examination. 4. Contrast noninvasive examination. 5. Physics of radioactivity. Radionuclides, most commonly used, their properties, examples of use. 6. Preparation of radionuclides in the reactor, cyclotron, theory. Description of the reactor, cyclotron, other accelerators. 7. Radiopharmaceuticals, species, their acquisition, generators. Methods of preparation of radioactive compounds. Kits for preparation radiopharmaceuticals, description of workplace preparation. Production, testing requirements. SPECT radiopharmaceuticals for individual examination. 8. PET radiopharmaceuticals, theory. Production, testing. The resulting image when using cameras. The most common PET pharmaceuticals and areas where they are used. Exercises - Excursion to the Nuclear Research Institute, Řež, a.s ..
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Learning activities and teaching methods
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- Contact hours
- 16 hours per semester
- Attendance on a field trip (number of real hours - maximum 8h/day)
- 8 hours per semester
- Preparation for comprehensive test (10-40)
- 20 hours per semester
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| prerequisite |
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| Knowledge |
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| are not required |
| Skills |
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| are not required |
| learning outcomes |
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| Knowledge |
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| describes the production and use of radiopharmaceuticals and contrast agents |
| Skills |
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| are not defined |
| teaching methods |
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| Knowledge |
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| Lecture |
| Skills |
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| Field trip |
| assessment methods |
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| Knowledge |
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| Test |
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Recommended literature
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Zákon č. 263/2016 Sb., atomovový zákon, ve znění zákona č. 183/2017 Sb..
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KOMÁREK, P., RABIŠKOVÁ, M., et al. Technologie léků: galenika. (Radiofarmaka).. Praha : Galén, 2006. ISBN 80-7262-423-7.
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MECHL, M. Metodický list intravaskulárního podání jodových kontrastních látek (JKL). Česká radiologie, 2007 vol. 61(1), s. 105-107..
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