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Lecturer(s)
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Horpeniak Radek, Doc. MUDr. Ph.D., MBA
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Course content
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1. Pathophysiology of pain - biochemical principles of pain formation, transmission of pain through individual levels of the peripheral and central nervous system. Peripheral and central mechanisms of pain. Endogenous opioids. 2. Types of pain - according to origin, duration, localization. Assessment and nature of pain. 3. Pain - deafferentation pain (anesthesia dolorosa), phantom pain, thalamic, root pain. 3. Pain - visceral, psychogenic, dysautonomic, neuropathic, transferred. 4. Pharmacotherapy of pain. 5. Affecting the sensitivity of nocisensors. Suppression of pain at the spinal level. 6. Thalamo-cortical level of pain influence. Affective influence of pain - hypothalamolimbic system. 7. Pain modulation 8. Pain pattern in oncological patients. 9. Principles of pharmacotherapy - current vs chronic pain 10. Vertebrogenic pain - nociceptive type, neuropathic type, psychogenic type, mixed type. 11. Non-pharmacological non-invasive pain management techniques. Placebo effect.
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Learning activities and teaching methods
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- Contact hours
- 22 hours per semester
- Preparation for comprehensive test (10-40)
- 20 hours per semester
- Preparation for formative assessments (2-20)
- 10 hours per semester
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| prerequisite |
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| Knowledge |
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| explain the difference between non-opioid and opioid analgesics |
| defines individual dosage forms and possible delivery routes for drug administration |
| Skills |
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| locate individual levels of the nervous system in connection with the transmission of a painful impulse |
| Competences |
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| N/A |
| learning outcomes |
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| Knowledge |
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| will explain the principle of pain at the biochemical level |
| will describe the transmission of the pain impulse through individual levels of the PNS and CNS |
| will clarify the role of endogenous opioids |
| describes the placebo effect |
| defines the possibilities of influencing pain at different levels |
| Skills |
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| classifies, characterizes and evaluates pain |
| distinguishes specific types of pain |
| Competences |
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| N/A |
| teaching methods |
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| Knowledge |
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| Lecture |
| Skills |
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| Task-based study method |
| Competences |
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| Lecture |
| Task-based study method |
| assessment methods |
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| Knowledge |
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| Test |
| Skills |
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| Continuous assessment |
| Competences |
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| Test |
| Continuous assessment |
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Recommended literature
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HAKL, M. Léčba bolesti: současné přístupy k léčbě bolesti a bolestivých syndromů. 4., dopl. vyd.. Praha: Maxdorf, 2022. ISBN 978-80-7345-727-3.
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Janáčková, Laura. Bolest a její zvládání. Vyd. 1. Praha : Portál, 2007. ISBN 978-80-7367-210-2.
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Rokyta, Richard. Bolest a jak s ní zacházet : učebnice pro nelékařské zdravotnické obory. Praha : Grada, 2009. ISBN 978-80-247-3012-7.
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